|
KMID : 1102220220410010043
|
|
Kidney Research and Clinical Practice
2022 Volume.41 No. 1 p.43 ~ p.57
|
|
|
Quality of life in patients with diabetic nephropathy: findings from the KNOW-CKD (Korean Cohort Study for Outcomes in Patients with Chronic Kidney Disease) cohort
|
|
Kim Hyun-Suk
Lee Joong-Yub
Choi Gwang-Ho
Jeong Hae-Min
Kim Seok-Hyung
Gu Jae-Eon
Yoo Jeong-Ju
Han Mi-Yeun
Kim Hyo-Jin
Sung Su-Ah
Han Seung-Hyeok
Kim Yeong-Hoon
Yoon Jong-Woo
Heo Jong-Ho
Oh Kook-Hwan
|
|
|
Abstract
|
|
|
Background: Diabetic nephropathy (DN) can affect quality of life (QoL) because it requires arduous lifelong management. This study analyzed QoL differences between DN patients and patients with other chronic kidney diseases (CKDs).
Methods: The analysis included subjects (n = 1,766) from the KNOW-CKD (Korean Cohort Study for Outcomes in Patients with Chronic Kidney Disease) cohort who completed the Kidney Disease Quality of Life Short Form questionnaire. After implementing propensity score matching (PSM) using factors that affect the QoL of DN patients, QoL differences between DN and non-DN participants were examined.
Results: Among all DN patients (n = 390), higher QoL scores were found for taller subjects, and lower scores were found for those who were unemployed or unmarried, received Medical Aid, had lower economic status, had higher platelet counts or alkaline phosphatase levels, or used clopidogrel or insulin. After PSM, the 239 matched DN subjects reported significantly lower patient satisfaction (59.9 vs. 64.5, p = 0.02) and general health (35.3 vs. 39.1, p = 0.04) than the 239 non-DN subjects. Scores decreased in both groups during the 5-year follow-up, and the scores in the work status, sexual function, and role-physical domains were lower among DN patients than non-DN patients, though those differences were not statistically significant.
Conclusion: Socioeconomic factors of DN were strong risk factors for impaired QoL, as were high platelet, alkaline phosphatase, and clopidogrel and insulin use. Clinicians should keep in mind that the QoL of DN patients might decrease in some domains compared with non-DN CKDs.
|
|
|
KEYWORD
|
|
|
Diabetic nephropathy, Kidney disease component summary, Kidney Disease Quality of Life Short Form questionnaire, Mental component summary, Physical component summary, Quality of life
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
   
|
|